Narcolepsy Risk DNA Test
$195.00
If you find it difficult to stay awake during the day or frequently experience involuntary naps, you may be at risk for narcolepsy. The Narcolepsy Risk DNA Test analyzes genetic factors that contribute to this sleep disorder.
- Assess genetic markers linked to narcolepsy risk.
- Easy, at-home cheek swab collection.
- Access your results securely online with full privacy.
Summary
What is Narcolepsy?
Narcolepsy is a chronic neurological disorder that affects the brain’s ability to regulate sleep-wake cycles. People with narcolepsy experience excessive daytime sleepiness and may suddenly fall asleep during the day, even in the middle of activities.
In more severe cases, individuals may also experience cataplexy, a sudden loss of muscle tone triggered by strong emotions, and disrupted nighttime sleep. While environmental and lifestyle factors contribute to narcolepsy, genetic predisposition plays a significant part in determining whether someone is at risk for developing the condition.
The Genetic Basis of Narcolepsy
Narcolepsy is closely linked to specific genetic factors, particularly the HLA-DQB1 gene. This gene is part of the human leukocyte antigen (HLA) system, which helps regulate the immune system. A specific variant of the HLA-DQB1 gene, known as HLA-DQB1 06:02, is strongly associated with narcolepsy. This variant increases susceptibility to the condition, especially in cases where narcolepsy involves cataplexy.
Although not everyone with this gene variant develops narcolepsy, nearly all individuals diagnosed with narcolepsy and cataplexy carry this genetic marker. The presence of HLA-DQB1 06:02 is considered a significant risk factor for the condition, and the Narcolepsy Risk DNA Test can identify whether you carry this variant.
The Narcolepsy Risk DNA Test
The Narcolepsy Risk DNA Test is designed to identify whether you carry the HLA-DQB1 06:02 variant, which is strongly associated with an increased risk of developing narcolepsy. This test can provide valuable insight into your genetic predisposition to narcolepsy, particularly if you are experiencing excessive daytime sleepiness, unusual sleep patterns, or other symptoms that may be related to the condition.
- Presence of HLA-DQB1 06:02: If the test shows that you carry this variant, it indicates a higher genetic risk for narcolepsy, particularly the type that includes cataplexy. However, the presence of this genetic marker does not guarantee the development of the condition. Other factors, such as immune system dysfunction or environmental triggers, also influence whether the condition manifests.
Absence of HLA-DQB1 06:02: If you do not carry this variant, your genetic risk for narcolepsy is lower. However, since narcolepsy can develop without this variant, the absence of HLA-DQB1 06:02 does not entirely rule out the possibility of narcolepsy.
The Narcolepsy Risk DNA Test offers insight into your genetic predisposition to narcolepsy by analyzing the HLA-DQB1 gene variant most closely associated with the condition. While the test results are not a diagnosis, they provide useful information that can support discussions with healthcare professionals regarding sleep health and potential narcolepsy symptoms.
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Why DNA Family Check?
With over 20 years of experience and a proven track record, DNA Family Check is the trusted leader in relationship DNA testing. Our high-volume accredited laboratory has helped millions of families worldwide find answers and resolve questions about their relationships. As pioneers in the industry, we were one of the first to introduce the easy cheek swab method that's now the industry standard.
With our longstanding commitment to excellence and innovation, it's no wonder we're America's #1 choice for paternity answers. Our accredited laboratory is dedicated to providing accurate, reliable, and confidential results, ensuring that families receive the truth they need to move forward. With DNA Family Check, you can trust that you're in good hands.
